Toxicokinetic studies allow you to describe the absorption, distribution, metabolism and excretion (ADME) of your chemical in an animal model. This information is important for a variety of reasons. It can allow you to relate concentrations of a chemical to observed toxicity, it establishes the main parent compound or metabolite in the circulation, gives information on potential accumulation in tissues and organs, and the chemical’s biotransformation. Data from toxicokinetic studies can be extrapolated for use in the assessment of human hazard and/or risk from your chemical.
Long history of conducting standard and tailored metabolism studies for a vast range of chemicals
An established team of metabolism scientists with scientific insights and practical expertise accumulated over years working in the industry
Flexible facilities that can accommodate a wide range of test species, to high welfare standards