What You Get
An inhalation toxicology team with extensive and diverse expertise
The inhalation toxicology team consists of a range of experts from diverse backgrounds and with extensive experience in planning and running inhalation toxicology studies. The team includes engineers, aerosol technologists, animal welfare specialists, vets, chemical analysts, pathologists and inhalation science toxicology experts.
Recognized inhalation studies delivered with reliable results
Our experience includes performing common inhalation toxicology studies such as:
- Acute to carcinogenicity
- Cardiotoxicity to assessing anesthetic potential
- Studies with specific approaches and dosing up to 24 hours/day
- Embryofetal to two-generation reproductive studies
Innovation to address your specific challenges and optimize results
Sometimes standard approaches don’t work — that’s when our ‘first of a kind’ inhalation toxicology mindset can help devise a solution suited to your unique challenge. This may be to address unusual endpoints or in the use of non-standard animal species. Alternatively, it may mean customizing inhalation delivery equipment to optimize data quality. This could be via custom-built inhalation chambers or even by 3D printing face masks specific to individual test animals. As your partner, Labcorp can innovate and enhance standard study approaches to optimize them for your chemical.
State-of-the-art analytical techniques and facilities to produce high-quality data
Working hand-in-hand with analytic scientists, the inhalation toxicology team ensures high quality data is produced in an appropriate timescale. Analytical approaches used include GC, IR, UPLC and HPLC analysis and compound specific analysis.
High welfare standards assured for a wide range of common and uncommon species
We are proud of the high welfare standards observed in all our in vivo work and especially in inhalation studies where a broad range of common and uncommon species may be required. An expert team of animal technicians and veterinarians conduct in vivo studies to ensure the highest levels of animal care. Inhalation studies can be performed on the following species:
- Pygmy goat
A comprehensive range of inhalation toxicology studies for your chemical
Our standard suite of inhalation toxicology studies for chemicals includes:
As well as standard studies, we can perform non-standard and tailored inhalation studies. Chronic toxicity and carcinogenicity and DART (developmental and reproductive toxicology) studies by the inhalation route are also available.
Chronic toxicity and carcinogenicity studies:
- OECD 414: Prenatal developmental toxicity study
- OECD 443: Extended one-generation reproductive toxicity study (EOGRTS)
- OECD 416: Two-generation reproduction toxicity
- OECD 421: Reproduction/developmental toxicity screening test
- OECD 422: Combined repeated dose toxicity study with the reproduction/developmental toxicity screening test